Headlines

Lab Headlines

2012

2/15/12: Prions play powerful role in the survival and evolution of wild yeast strains (Whitehead Institute)
2/15/12: Prions and chaperones: Outside the fold, by Bijal P. Trivedi, Nature
1/26/12: Susan Lindquist delivers Rosalind Franklin Lecture at Kings College London (King's Health Partners)

2011

10/31/11: High levels of master heat shock protein linked to poor prognosis in breast cancer patients (Whitehead Institute)
10/27/11: Yeast model connects Alzheimer's disease risk and amyloid beta toxicity (Whitehead Institute)
10/20/11: Susan Lindquist elected to EMBO
07/08/11: "Opposing effects of glutamine and asparagine govern prion formation by intrinsically disordered proteins," by Halfmann et al., published in Molecular Cell
07/07/11: Lindquist Lab researchers win Whitehead Spirit Awards: Brooke Bevis, go-to person; Lera Baru, unsung hero
05/16/11: Dr. Susan Lindquist: On the Cusp (WTMA Lecture, Angelo State Univ, ASU Headlines)
05/11/11: Undergraduate researchers win MIT Biology Awards: Amelia Chang, Merck prize; Christine Hazlett, John L. Asinary Award
03/22/11: Understanding Proteins: New model of protein folding helps researchers handle flood of genomic data by Larry Hardesty (MIT News)
03/11/11: Futures in Biotech 7: How The Environment And A Single Protein Influence Evolution (TWiT podcast)
03/11/11: Former Lindquist ExROP student Sandra Jones wins Gilliam Fellowship (HHMI News)
03/01/11: Whitehead Named Best Place to Work for postdocs, 2011 (The Scientist)
01/26/11: Protein-only mechanism drives Aplysia molecular memory (Heinrich & Lindquist PNAS)

2010

12/23/10: Heat shock protein drives yeast evolution (Whitehead Institute)
11/28/10: Optical Trapping Reveals Unexpected Behaviors of Prion Fibers (Dong et al. Nature Mol Cell Biol)
11/18/10: Susan Lindquist awarded National Medal of Science (MIT News)
12/23/10: Heat shock protein drives yeast evolution (Whitehead Institute)
06/22/10: Bubbles, Bread, and Beer by Olivia Judson (New York Times Opinionator)
04/26/10: A different tune: cellular IPOD plays role in prion biology (Whitehead Institute)

2009

12/28/09: Small molecules found to protect cells in multiple models of Parkinson's disease
08/26/09: Gene mutation alone causes transmissible prion disease
07/13/09: New method may accelerate drug discovery for difficult diseases like Parkinson's
05/22/09: Lindquist Lab Documentary: Asking Yeast About Parkinson Disease (MIT TechTV)
04/13/09: Local companies delve deep into cell origami
04/01/09: Redefining what it means to be a prion
02/22/09: Calculating gene and protein connections in a Parkinson’s model
02/09/09: The Hsp90-antifungal combo, please: Compromising fungi in the immunocompromised
02/01/09: Study reveals connection between genetic and environmental causes of Parkinson’s disease

2008

12/08: Nature selects Hsp90 & evolution as one of the 15 evolutionary gems published in the journal in the last couple of decades (#15 "Variation vs. Stability")
12/08: Meet JoVE: The YouTube Of Scientific Journals by Zeina Siam (The Tech, online edition)
11/08: Misfolded proteins accelerate yeast evolution (Whitehead Institute)
11/08: Prion switching in response to environmental stress (News Release, PLoS Biology)
11/08: New clue emerges for cellular damage in Huntington's Disease (Whitehead Institute)
11/08: HHMI pilot program funds people and a few projects by Elizabeth Cooney (White Coat Notes, News from the Boston-area medical community)
10/08: Interplay of heat shock proteins regulates prion formation (Shorter & Lindquist EMBO)
09/08: Heat shock factor 1 regulates lifespan in prion disease (Steele et al. PNAS)
07/08: Susan Lindquist Honored with FASEB Excellence in Science Award
06/08: Susan Lindquist Honored with Harvard Centennial Medal
05/08: Susan Lindquist presents "New Clues to Parkinson's Disease from an Unlikely Source" to the Congressional Biomedical Research Caucus in Washington DC
04/08: Mechanism for protecting yeast cells from prion toxicity (Douglas, Treusch et al. PNAS)
03/08: Susan Lindquist receives Otto Warburg Prize
03/08: Parkinson's disease cellular processes revealed by yeast model (Gitler et al. PNAS)
01/08: Lindquist Wins 2008 Genetics Society of America Medal
01/08: Hsp90-buffered genetic variation influences evolution of new traits (Sangster et al. PNAS 2008 a) (Sangster et al. PNAS 2008 b)

2007

12/07: HSF1/cancer biology paper selected as one of Nature's Research Highlights for 2007 (Dai et al. Cell)
09/07: Susan Lindquist Named one of Harvard's 100 Most Influential Alumni "The Harvard 100," 02138 Magazine
09/21/07: Heat Shock Factor 1 Is a Powerful Multifaceted Modifier of Carcinogenesis (Dai et al, Cell)

Heat Shock Proteins Are Co-opted for Cancer, by Deborah Halber (Whitehead Institute)
Cancer Cells Chill Out to Survive, by Mitch Leslie (ScienceNOW Daily NEWS)
Ancient mechanism for coping with stresses also gives cancer a boost (Cell Press)
HSF1 Inhibition Helps Fight Cancer Growth (Genetic Engineering & biotechnology News, GEN News Highlights)

05/09/07: Prion recognition elements govern nucleation, strain specificity and species barriers [Tessier et al. Nature], [Supplementary Information]
- Scientists Closer to Unfolding Mysteries of Prion Formation in Mad Cow Disease, by Nikhil Swaminathan (Scientific American)
- Scientists identify prion's infectious secret, by David Cameron (Whitehead Institute)
- Researchers Identify Key Elements Controlling Prion Formation (HHMI Research News)
01/29/07: Lab neurodegenerative disease research published in PNAS, highlighting new high-throughput mouse behavioral phenotyping technology (Steele et al., PNAS)
01/24-28/2007: Susan Lindquist leads sessions on biotechnology at the World Economic Forum in Davos, Switzerland

2006

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12/11/06: Parkinson's disease process may be curtailed by regenerative processes in yeast, fruit flies (MIT News)
11/12/06: Susan Lindquist named in Scientific American's "SA50, Trends in Business, Policy and Research"
11/01/06: Lindquist Research chosen for What a Year! (November) by the Massachusetts Society for Medical Research
- Folding Proteins, Michael J. Fox and Parkinson's Disease. What do they have in common?
10/09/06: Susan Lindquist elected to the Institute of Medicine of the National Academies
07/21/06: "α-Synuclein Blocks ER-Golgi Traffic and Rab1 Rescues Neuron Loss in Parkinson’s Models" (Abstract) (Reprint) published in Science
07/18/06: Huntington's Disease Research Published in PNAS. [PDF 1.29 MB], [PDF 1.46 MB]
06/23/06:
- Lindquist discusses her Science paper Morning Edition and Science Friday
- Parkinson's traits reversed in rat brain cells (New Scientist)
- Protecting Neurons from Parkinson's Disease (Technology Review)
05/09/06: Susan Lindquist Inaugurates "Futures in Biotech" Podcast on TWiT Network