Postdoctoral Associates and Fellows |
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Simon Alberti, PhD |
Rm# 651 |
alberti at wi.mit.edu | Simon is investigating the impact of prion-based mechanisms on the biology and evolution of yeast. |
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Pavan Auluck, MD, PhD |
Rm# 649 |
auluck at wi.mit.edu | Pavan is interested in models of neurodegenerative disease. |
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Gabriela Caraveo, PhD |
Rm# 649 |
caraveop at wi.mit.edu | Gabriela is working on identifying genetic modifiers of cellular toxicity in a yeast Parkinson model. |
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Jijun Dong, PhD |
Rm# 659 |
jdong at wi.mit.edu | Jijun is investigating the mechanics and structures of yeast amyloid fibers by optical tweezers. |
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William Kaya Erbil, PhD |
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erbil at wi.mit.edu | Kaya is developing individual cell-based imaging systems for yeast and neuronal cells, in collaboration with Jeff Gore in the MIT Physics Department. |
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Kendra K. Frederick, PhD |
Rm# 657 |
kendrakf at wi.mit.edu | Kendra is investigating the mechanism of NM oligomer and fiber formation by NMR. |
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Melissa Geddie, PhD |
Rm# 649 |
geddie at wi.mit.edu | Melissa is working on modifiers of alpha-synuclein toxicity. |
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Sven Heinrich, PhD |
Rm# 659 |
heinrich at wi.mit.edu | Sven is interested in investigation of the mechanism and identification of new regulators of prion formation of neuronal CPEB. |
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Walker Jackson, PhD |
Rm# 655 |
wjackson at wi.mit.edu | Walker is interested in why different mutations to the mammalian prion protein gene cause different neurodegenerative diseases. |
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Daniel Jarosz, PhD |
Rm# 653 |
jarosz at wi.mit.edu | Dan J. is interested in the mechanisms by which Hsp90 influences the expression of phenotypic variation and allows new traits to become genetically fixed. |
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Rajaraman Krishnan, PhD |
Rm# 655 |
krishnan at wi.mit.edu | Ram is investigating the interactions of Hsp104p with the yeast Sup35p and Rnq1p. |
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Catherine McLellan, PhD |
Rm# 649 |
mclellan at wi.mit.edu | Catherine is interested in the modulation of function of cancer related proteins by Hsp90. |
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Marc Mendillo, PhD |
Rm# 653 |
mendillo at wi.mit.edu | Marc is a studying the role of the heat shock response in cancer. |
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Elena Nabieva, PhD |
Rm# 655 |
nabieva at wi.mit.edu | Elena is a computational biologist analyzing data from a variety of disease model systems and screens. |
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Christopher Pacheco, PhD |
Rm# 657 |
pacheco at wi.mit.edu | Chris is working on Parkinson disease-related genes in collaboration with Dr. Richard Myers. |
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Lauren Pepper, PhD |
Rm# 653 |
pepper at wi.mit.edu | Lauren is working on N-rich proteins in malaria. |
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Sandro Santagata, MD, PhD |
Rm# 657 |
santagat at wi.mit.edu | Sandro is interested in using the heat shock response as a sensor for bioactive molecules that can be used to treat brain tumors. |
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Mikko Taipale, PhD | Rm# 655 | taipale at wi.mit.edu | Mikko is investigating how Hsp90 modulates the relationship between genotype and phenotype in human cancer cells. |
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Daniel Tardiff, PhD | Rm# 653 | tardiff at wi.mit.edu | Dan Tardiff is using yeast and neuronal models to study modulators of TDP-43 proteinopathy. |
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Daniel Termine, PhD | Rm# 653 | termine at wi.mit.edu | Dan Termine is interested in biochemical pathways in cellular toxicity in neurodegenerative disease. |
Senior Research Scientists
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Chee-Yeun Chung, PhD |
Rm# 649 |
cychung at wi.mit.edu |
Chee-Yeun is studying mechanisms of cell death in dopaminergic neurons. |
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Luke Whitesell, MD |
Rm# 663 |
whitesell at wi.mit.edu |
Luke is interested in preventing cancer from being triggered or progressing by targeting cellular stress responses and the molecular chaperones regulated by them. |
Staff Scientist
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Kent Matlack, PhD |
Rm# 651 |
kmatlack at wi.mit.edu | Kent is interested in developing new yeast models of neurodegenerative diseases, including ALS and Alzheimer's. |
Visiting Scientist
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Vikram Khurana, MD, PhD |
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khurana at wi.mit.edu | Vik is interested in stem cell-based therapeutics for neurodegenerative diseases and is collaborating with the laboratory of Rudolf Jaenisch. |
Graduate Students
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Randal Halfmann |
Rm# 651 |
halfmann at wi.mit.edu | Randal is identifying new prions in yeast and examining how they influence yeast evolution. |
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Charles O'Donnell
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Rm# 635 |
cwo at mit.edu | Charlie is working on algorithms for investigating NM structure. Charlie is co-mentored by Bonnie Berger in the Department of Applied Mathematics at MIT. |
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Sebastian Treusch |
Rm# 653 |
treusch at wi.mit.edu | Sebastian is interested in identifying and characterizing proteins that are required to induce and maintain [RNQ+] and potentially other yeast prions. |
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Julie Valastyan |
Rm# 659 |
beckenst at wi.mit.edu | Julie is working on factors that influence the toxicity of the human Parkinson's disease-asspciated protein, alpha-synuclein, in yeast. |
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Benjamin Vincent |
Rm# 649 |
bvincent at wi.mit.edu | Ben is probing the heat shock response and the evolution of drug resistance through the characterization of novel small molecules. |
Undergraduate Students
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Stephanie Bachar MIT UROP Class of 2011 |
Rm# 653 |
bachar at mit.edu |
Stephanie is characterizing Hsp90-dependent genes and phenotypes in yeast. |
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Christine Hazlett MIT UROP Class of 2011 |
Rm# 657 |
hazlett at wi.mit.edu |
Christine is studying mechanisms of amyloid fiber formation. |
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Richard Manfready MIT UROP Class of 2011 |
Rm# 649 |
ram at wi.mit.edu |
Richard is assessing the role of polyamine transport proteins in the cytotoxic mechanism of alpha-synuclein. |
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Ambar Mehta MIT UROP Class of 2012 |
Rm# 659 |
ambar91 at mit.edu |
Ambar is investigating the differential effects of nutritional sources on alpha-synuclein toxicity. |
Technical Associates
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Valeriya Baru |
Rm# 641 |
baru at wi.mit.edu | Lera works on biochemistry and molecular biology of human diseases, and differentiation of mouse ES cells. |
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Yelena Freyzon |
Rm# 637 |
freyzon at wi.mit.edu | Yelena works on in vivo and in vitro models of human diseases and manages the lab mouse colony. |
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Haesun Han |
Rm# 655 |
han at wi.mit.edu | Haesun works on high-throughput screening in yeast models of neurodegenerative disease. |
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Ed Hyoungtae Kwon |
Rm# 657 |
kwonh at wi.mit.edu | Ed works on heat shock proteins and cancer biology. |
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Artur Topolszki |
Rm# 655 |
artur at mit.edu | Artur is a vital member of ongoing projects to determine the normal function of PrP, the role of several genes in prion disease, and the study of PrP mutant induced toxicity in mice. |
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Melissa Topolszki |
Rm# 655 |
duquette at mit.edu | Melissa is helping out with a variety of projects in the lab, including but not limited to studies of heat shock factor one (HSF1) in cancer. |
Lab Manager
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Brooke Bevis, PhD |
Rm# 659 |
bevis at wi.mit.edu | Brooke is classifying and characterizing modifiers of toxicity in the yeast Parkinson's disease model. |
Executive Assistant
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Kate Harmon, M.Ed., M.B.A. |
Rm# 661 |
harmon at wi.mit.edu | Kate coordinates communication within the lab and between the members of lab and the outside world. She assists Dr. Lindquist and members of the lab with scheduling, travel arrangements, record keeping, purchasing, document preparation and general lab administration. |
Lab Administrator
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Robert Burger |
Rm# 661 |
burger at wi.mit.edu | Bob performs financial accounting, ordering, and personnel management for the Lindquist and Matsudaira labs, and liaisons with the Office of Sponsored Programs. |
Project Manager, Communications and Grant Development
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Karen Allendoerfer, PhD |
Rm# 663 |
allendoe at wi.mit.edu | Karen manages communication and development of scientific activities for the Lindquist Lab. She manages and assists in the preparation of scientific aspects of grants and fellowships, edits manuscripts, and maintains the lab website. |