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March
2005
Announcement
of The RNAi Consortium (TRC)
February 2005
Publication
of Paper Reporting Discovery of Rictor-mTOR as a hydrophobic motif
kinase of Akt/PKB
December 2003
David
Sabatini named Charles Ross Scholar by MIT
July
29, 2003
David
Guertin wins a Damon Runyon Fellowship
Additional links: Damon
Runyon Fellowship Award
April 25, 2003
Publication
of Article Reporting Discovery of GbL, a New Component of the mTOR
Signaling Complex - Like raptor, GbL is a critical component
of the mTOR signaling complex and is required for cell growth in
mammalian cells. The protein consists of seven WD-40 repeats and
is similar to the beta subunits of heterotrimeric G-proteins. It
binds and activates the mTOR kinase domain and also facillitates
the interaction of raptor with mTOR. An article describing these
findings was published today in Molecular Cell with Do-Hyung Kim
as lead author. Additional links: NCBI;
UPI
story; ScienceDaily
story
July 26, 2002
Publication of Article Describing Raptor, a Novel Protein that Interacts
with mTOR
Since the discovery of mTOR in the 1994 it has been clear that
the protein is likely part of a large complex within cells. However,
we and others have failed to identify other components of this complex.
We now report the discovery of raptor, the first protein identified
that interacts with mTOR in a near stoichiometric ratio and that
appears to be an integral component of the mTOR signaling complex.
An article describing these findings was published today in Cell
with Do-Hyung Kim as lead author. Additional link: NCBI
July 16, 2002
David
Sabatini Named One of the World's Top Young Innovators by Technology
Review, MIT's Magazine of Innovation - The Whitehead Institute
for Biomedical Research today announced that David Sabatini has
been chosen as one of the world’s 100 Top Young Innovators
by Technology Review, MIT’s Magazine of Innovation. The TR100,
chosen by Technology Review, MIT’s award-winning magazine
of innovation, consists of 100 young individuals whose innovative
work in business and technology has a profound impact on today’s
world. Nominees are recognized for their contribution in transforming
the nature of technology in industries such as biotechnology, computing,
energy, medicine, manufacturing, nanotechnology, telecommunications
and transportation.
October 3, 2002
BioMedNet
Story about Steve Bailey's Presentation at BioArrays Europe
- Steve gives a talk at the BioArrays Europe meeting in Cambridge,
U.K. In a news story covering the talk Steve is given the fanciful
position of 'Senior Member of the Whitehead Institute's microarray
division'. Somehow, there is no mention that he works in the Sabatini
and Stockwell labs.
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