Publications
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Publications |
Odom D.T., Zizlsperger, N., Gordon D.B., Bell G.W., Rinaldi N.J., Murray H.L., Volkert T.L., Schreiber J., Rolfe P.A., Gifford D.K., Fraenkel E., Bell G.I., Young R.A.
Control of Pancreas and Livere Gene Expression by HNF Transcription Factors. Science 303: 1378-81 (2004).
[Abstract] [Full text] [Website]
Izmailova E., Bertley F.M., Huang Q., Makori N., Miller C.J., Young R.A., Aldovini A.
HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages. Nat Med. 2003 Feb;9(2):163-4.
[Abstract]
[Full text]
Zeitlinger, J., Simon, I., Harbison, C.T., Hannett, N.M., Volkert, T.L., Fink, G.F. and Young, R.A.
Program-specific distribution of a
transcription factor dependent on partner transcription factor and MAPK
signaling. Cell 113:395-404 (2003).
[Abstract]
[Full text]
[Website]
Ng H.H., Robert F., Young R.A., Struhl K.
Targeted Recruitment of Set1 Histone Methylase by Elongating Pol II Provides a Localized Mark and Memory of Recent Transcriptional Activity. Mol. Cell 11(3):709-19 (2003).
[Abstract] [Full text]
[Website]
Lee, T.I., Rinaldi, N.J., Robert, F., Odom, D.T., Bar-Joseph, Z., Gerber, G.K., Hannett, N.M., Harbison, C.R., Thompson, C.M., Simon I., Zeitlinger J., Jennings, E.G., Murray, H.L., Gordon, D.B., Ren, B., Wyrick, J.J., Tagne, J., Volkert T.L., Fraenkel, E., Gifford D.K., and Young, R.A.
Transcriptional Regulatory Networks in Saccharomyces cerevisiae. Science 298: 799-804 (2002).
[Abstract] [Free full text] [Website]
Pokholok, D.K., Hannett, N.M., and Young, R.A.
Exchange
of RNA Polymerase II Initiation and Elongation Factors during Gene
Expression In Vivo. Mol. Cell 9:799-809 (2002).
Ng, H.H., Robert, F., Young, R.A., and Struhl, K.
Genome-wide
Location and Regulated Recruitment of the RSC
Nucleosome-remodeling Complex. Genes Dev. 16:806-819
(2002).
Damelin, M., Simon, I., Moy, T.I., Wilson, B., Komili, S.,
Tempst, P., Roth, F.P., Young, R.A., Cairns, B.R., and Silver,
P.A.
The
Genome-Wide Localization of Rsc9, a Component of the RSC
Chromatin-Remodeling Complex, Changes in Response to Stress. Mol.
Cell 9:563-73 (2002).
Hartemink, A.J., Gifford, D.K., Jaakkola, T.S., and Young,
R.A.
Combining
Location and Expression Data for Principled Discovery of Genetic
Regulatory Network Models. Pac. Symp. Biocomput. 6:437-449
(2002).
Wyrick, J.J. and Young, R.A.
Deciphering
Gene Expression Regulatory Networks. Curr. Opin. Genet. Dev.
12:130-136 (2002).
Ren, B., Cam, H., Takahashi, Y., Volkert, T., Terragni, J.,
Young, R.A., and Dynlacht, B.D.
E2F
Integrates Cell Cycle Progression with DNA Repair, Replication,
and G2/M Checkpoints. Genes Dev. 16:245-256 (2002).
Causton, H.C., Ren, B., Koh, S.S., Harbison, C.T., Kanin, E.,
Jennings, E.G., Lee, T., True, H.L., Lander, E.S., and Young,
R.A.
Remodeling
of Yeast Genome Expression in Response to Environmental Changes.
Mol. Biol. Cell 12:323-337 (2001).
Chi, Y., Huddleston, M.J., Zhang, X., Young, R.A., Annan, R.S.,
Carr, S.A., and Deshaies, R.J.
Negative
Regulation of Gcn4 and Msn2 Transcription Factors by Srb10
Cyclin-Dependent Kinase. Genes Dev. 15:1078-1092
(2001).
Geisberg, J.V., Holstege, F.C., Young, R.A., and Struhl, K.
Yeast
NC2 Associates with the RNA Polymerase II Preinitiation Complex
and Selectively Affects Transcription In Vivo. Mol. Cell. Biol.
21:2736-2742 (2001).
Hartemink, A.J., Gifford, D.K., Jaakkola, T.S., and Young,
R.A.
Using
Graphical Models and Genomic Expression Data to Statistically
Validate Models of Genetic Regulatory Networks. Pac. Symp.
Biocomput. 6:422-433 (2001).
Simon, I., Barnett, J., Hannett, N., Harbison, C.T., Rinaldi,
N.J., Volkert, T.L., Wyrick, J.J., Zeitlinger, J., Gifford, D.K.,
Jaakkola, T.S. and Young, R.A.
Serial
Regulation of Transcriptional Regulators in the Yeast Cell Cycle.
Cell 106:697-708 (2001).
Virbasius, C.A., Holstege, F.C., Young, R.A., and Green,
M.R.
Promoter-specific
Activation Defects by a Novel Yeast TBP Mutant Compromised for
TFIIB Interaction. Curr. Biol. 11:1794-1798 (2001).
Wyrick, J.J., Aparicio, J.G., Chen, T., Barnett, J.D.,
Jennings, E.G., Young, R.A., Bell, S.P., and Aparicio, O.M.
Genome-Wide
Distribution of ORC and MCM Proteins in S. cerevisiae:
High-Resolution Mapping of Replication Origins. Science
294:2357-2360 (2001).
Zaman, Z., Ansari, A.Z., Koh, S.S., Young, R., and Ptashne
M.
Interaction
of a Transcriptional Repressor with the RNA Polymerase II
Holoenzyme Plays a Crucial Role in Repression. Proc. Natl. Acad.
Sci. USA 98:2550-2554 (2001).
Lee, T., Causton, H.C., Holstege, F.C.P, Shen, W.-C., Hannett,
N., Jennings, E.G., Winston, F., Green, M.R. and Young, R.A.
Redundant
Roles for the TFIID and SAGA Complexes in Global Transcription.
Nature 405:701-704 (2000).
Lee, T. and Young, R.A.
Transcription
of Eukaryotic Protein-coding Genes. Ann. Rev. Genet. 34:77-137
(2000). (additional
references)
Ren, B., Robert, F., Wyrick, J.J., Aparicio, O., Jennings,
E.G., Simon, I., Zeitlinger, J., Schreiber, J., Hannett, N.,
Kanin, E., Volkert, T.L., Wilson, C.J., Bell, S.P., and Young,
R.A.
Genome-wide
Location and Function of DNA Binding Proteins. Science
290:2306-2309 (2000).
Robertson, L.S., Causton, H.C., Young, R.A. and Fink, G.R.
The
Yeast A Kinases Differentially Regulate Iron Uptake and
Respiratory Function. Proc. Natl. Acad. Sci. USA 97:5984-5988
(2000).
Young, R.A.
Biomedical
Discovery with DNA Arrays. Cell 102:9-15 (2000)
Holstege, F.C.P. and Young, R.A.
Transcriptional
regulation: Contending with Complexity. Proc. Natl. Acad. Sci. USA
96:2-4 (1999).
Jennings, E.G. and Young, R.A.
Genome
expression on the World Wide Web. Trends Genet. 15:202-204
(1999).
Kimmelman, J., Kaldis, P., Hengartner, C.J., Laff, G.M., Koh,
S.S., Young, R.A. and Solomon, M.J.
Activating
Phosphorylation of the Kin28p Subunit of TFIIH by the Cdk
Activating Kinase, Cak1p. Mol. Cell. Biol. 19:4774-4787
(1999).
Kobor, M.S., Archambault, J., Lester,W., Holstege, F.C.P.,
Gileadi, O., Jansma, D., Jennings, E.G., Kouyoumdjian, F.,
Davidson, A.R., Young, R.A. and Greenblatt, J.
A
Novel Protein Phosphatase Required for Dephosphorylation of the
CTD and Transcription by RNA polymerase II in Saccharomyces
cerevisiae. Mol. Cell 4:55-62 (1999).
Tudor, M., Murray, P.J., Onufryk, C., Jaenisch, R. and Young,
R.A.
Ubiquitous
Expression and Embryonic Requirement for RNA Polymerase II
Coactivator Subunit Srb7 in Mice. Genes Dev. 13:2365-2368
(1999).
Viljoen, M., Volschenk, H., Young, R.A. and van Vuuren,
H.J.J.
Transcriptional
Regulation of the Schizosaccharomyces pombe Malic Enzyme
Gene, mae2. J. Biol. Chem. 274:9969-9975 (1999).
Wyrick, J.J., Holstege, F.C.P., Jennings, E.G., Causton, H.C.,
Shore, D., Grunstein, M., Lander, E.S. and Young, R.A.
Chromosomal
Landscape of Nucleosome-dependent Gene Expression and Silencing in
Yeast. Nature 402:418-421 (1999).
Apone, L.M., Virbasius, C.A., Holstege, F.C.P., Wang, J.,
Young, R.A. and Green, M.R.
Broad,
but Not Universal, Transcriptional Requirement for yTAFII17, a
Histone H3-like TAFII Present in TFIID and SAGA. Mol. Cell
2:653-661 (1998).
Hengartner, C.J., Myer, V.E., Liao, S.-M., Wilson, C.J., Koh,
S.S. and Young, R.A.
Temporal
Regulation of RNA Polymerase II by Srb10 and Kin28
Cyclin-Dependent Kinases. Mol. Cell 2:43-53 (1998).
Holstege, F.C.P., Jennings, E.G., Wyrick, J.J., Lee, T.,
Hengartner, C.J., Green, M.R., Golub, T.R., Lander, E.S. and
Young, R.A.
Dissecting
the Regulatory Circuitry of a Eukaryotic Genome. Cell 95:717-728
(1998).
Koh, S.S., Ansari, A.Z., Ptashne, M. and Young, R.A.
An
Activator Target in the RNA Polymerase II Holoenzyme. Mol. Cell
1:895-904 (1998).
Lee, T., Wyrick, J.J., Koh, S.S., Jennings, E.G., Gadbois, E.L.
and Young, R.A.
Interplay
of Positive and Negative Regulators in Transcription Initiation by
RNA Polymerase II Holoenzyme. Mol. Cell. Biol. 18:4455-4462
(1998).
Lee, T. and Young, R.A.
Regulation
of Gene Expression by TBP-associated Proteins. Genes Dev.
12:1398-1408 (1998).
Myer, V.E. and Young, R.A.
RNA
Polymerase II Holoenzymes and Subcomplexes. J. Biol. Chem.
273:27757-27760 (1998).
Parvin, J.D. and Young, R.A.
Regulatory
Targets in the RNA Polymerase II Holoenzyme. Curr. Op. Genet. Dev.
8:565-570 (1998).
Gadbois, E.L., Chao, D.M., Reese, J.C., Green, M.R. and Young,
R.A.
Functional
antagonism between RNA polymerase II holoenzyme and global
negative regulator NC2 in vivo. Proc. Natl. Acad. Sci. USA 94:
3145-3150 (1997).
Koh, S.S., Hengartner, C.J. and Young, R.A.
Baculoviral
transfer vectors for expression of FLAG fusion proteins in insect
cells. Biotechniques 23:622-624 (1997).
Qin, J., Fenyo, D., Zhao, Y., Hall, W.W., Chao, D.M., Wilson,
C.J., Young, R.A. and Chait, B.T.
A
strategy for rapid, high-confidence protein identification. Anal
Chem 69:3995-4001 (1997).
Scully, R., Anderson, S.F., Chao, D.M., Wei, W., Ye, L., Young,
R.A., Livingston, D.M. and Parvin, J.D.
BRCA1
is a component of the RNA polymerase II holoenzyme. Proc. Natl.
Acad. Sci. USA 94: 5605-5610 (1997).
Sune, C., Hayashi, T., Liu, Y., Lane, W.S., Young, R.A. and
Garcia-Blanco, M.A.
CA150,
a nuclear protein associated with the RNA polymerase II
holoenzyme, is involved in Tat-activated human immunodeficiency
virus type 1 transcription. Mol Cell Biol 17: 6029-6039
(1997).
Volschenk, H., Viljoen, M., Grobler, J., Petzold, B., Bauer,
F., Subden, R.E., Young, R.A., Lonvaud, A., Denayrolles, M. and
van Vuuren, H.J.
Engineering
pathways for malate degradation in Saccharomyces cerevisiae. Nat
Biotechnol 15: 253-257 (1997).
Chao, D.M., Gadbois, E.L., Murray, P.J., Anderson, S.F., Sonu,
M.S., Parvin, J.D., and Young, R.A.
A
mammalian SRB protein associated with an RNA polymerase II
holoenzyme. Nature 380: 82-85 (1996).
Koleske, A.J., Chao, D.M. and Young, R.A.
Purification
of RNA polymerase II holoenzymes. Methods Enzymol. 273: 176-184
(1996).
Rubin, D.M., Coux, O., Wefes, I., Hengartner, C., Young, R.A.,
Goldberg, A.L. and Finley, D.
Identification
of the gal4 suppressor Sug1 as a subunit of the yeast 26S
proteosome. Nature 374: 655-657 (1996).
Wilson, C.J., Chao, D.M., Imbalzano, A.N., Schnitzler, G.R.,
Kingston, R.E. and Young, R.A.
RNA
polymerase II holoenzyme contains SWI/SNF coactivators involved in
chromatin remodeling. Cell 84: 235-244 (1996).
Hengartner, C., Thompson, C.M., Zhang, J., Chao, D.M., Liao,
S-M., Koleske, A.J., Okamura, S. and Young, R.A.
Association
of an activator with an RNA polymerase II holoenzyme. Genes &
Dev. 9: 897-910 (1995).
Koleske, A.J. and Young, R.A.
The RNA polymerase II holoenzyme and its implications for gene
regulation. Trends Biochem. Sci. 20: 113-116 (1995)
Liao, S-M., Zhang, J., Jeffery, D., Koleske, A.J., Thompson,
C.M., Chao, D.M., Viljoen, M., van Vuuren, H.J.J. and Young,
R.A.
A
kinase-cyclin pair in the RNA polymerase II holoenzyme. Nature
374: 193-196 (1995).
Serizawa, H., Makela, T. P., Conaway, J.W., Conaway, R.C.,
Weinberg, R.A. and Young, R.A.
Association
of CDK-activating kinase subunits with transcription factor TFIIH.
Nature 374: 280-282 (1995).
Thompson, C.M. and Young, R.A.
General
requirement for RNA polymerase II holoenzymes in vivo. Proc. Natl.
Acad. Sci. USA 92: 4587-4590 (1995).
Koleske, A.J. and Young, R.A.
An
RNA polymerase II holoenzyme responsive to activators. Nature 368:
466-469 (1994).
Woychik, N.A. and Young, R.A.
Exploring RNA polymerase II structure and function. in:
Transcription: Mechanisms and Regulation, (R.C. Conaway and J.W.
Conaway, eds.) Raven Press, New York, pp. 227-242 (1994).
Choder, M. and Young, R.A.
A
portion of RNA polymerase II molecules have a component essential
for stress responses and stress survival. Mol. Cell. Biol. 13:
6984-6991 (1993).
McKune, K., Richards, K.L., Edwards, A.M., Young, R.A. and
Woychik, N.A.
RPB7,
one of two dissociable subunits of RNA polymerase II, is essential
for yeast cell viability. Yeast 9: 295-299 (1993).
Thompson, C.M., Koleske, A.J., Chao, D.M. and Young, R.A.
A
multisubunit complex associated with the RNA polymerase II CTD and
TATA binding protein in yeast. Cell 73: 1361-1375
(1993).
Woychik, N.A., McKune, K., Lane, W.S. and Young, R.A.
Yeast
RNA polymerase II subunit RPB11 is related to a subunit shared by
RNA polymerase I and III. Gene Express. 3: 77-82
(1993).
Bowen, A.R., Chen-Wu, J., Momany, M., Young, R., Szaniszlo,
P.J. and Robbins, P.W.
Classification
of fungal chitin synthases. Proc. Natl. Acad. Sci. USA 89: 519-523
(1992).
Koleske, A.J., Buratowski, S., Nonet, M. and Young, R.A.
A
novel transcription factor reveals a functional link between the
RNA polymerase II CTD and TFIID. Cell 69: 883-894
(1992).
Woychik, N. and Young, R.A.
Genes
encoding transcription factor IIIA and the RNA polymerase common
subunit RPB6 are divergently transcribed in Saccharomyces
cerevisiae. Proc. Natl. Acad. Sci. USA 89: 3999-4003
(1992).
Chao, D. and Young, R.A.
Tailored
tails and transcription initiation: the carboxyl terminal domain
of RNA polymerase II. Gene Express. 1: 1-4 (1991).
Edwards, A.M., Kane, C.M., Young, R.A. and Kornberg, R.D.
Two
dissociable subunits of yeast RNA polymerase II stimulate the
initiation of transcription at a promoter in vitro. J. Biol. Chem.
266: 71-75 (1991).
Hekmatpanah, D. and Young, R.A.
Mutations
in a conserved region of RNA polymerase II influence the accuracy
of mRNA start site selection. Mol. Cell. Biol. 11: 5781-5791
(1991).
Kolodziej, P. and Young, R.A.
Epitope
tagging and protein surveillance. Methods Enzymol. 194: 508-519
(1991).
Kolodziej, P. and Young, R.A.
Mutations
in the three largest subunits of yeast RNA polymerase II that
affect enzyme assembly. Mol. Cell. Biol. 11: 4669-4678
(1991).
Liao, S.-M., Taylor, I.C.A., Kingston, R.E. and Young, R.A.
RNA
polymerase II C-terminal domain contributes to the response to
multiple acidic activators in vitro. Genes Dev. 5: 2431-2440
(1991).
Woychik, N., Lane, W.S. and Young, R.A.
Yeast
RNA polymerase II subunit RPB9 is essential for growth at
temperature extremes. J. Biol. Chem. 266: 19053-19055
(1991).
Young, R.A.
RNA Polymerase II. Ann. Rev. Biochemistry 60: 689-715
(1991).
Molecular Biology and Immunology of Infectious Diseases
Nau, G.J., Richmond, J.F.L., Schlesinger, A., Jennings, E.G.,
Lander, E.S., and Young, R.A.
Human
Macrophage Activation Programs Induced by Bacterial Pathogens.
Proc. Natl. Acad. Sci. USA 99:1503-1508 (2002).
Huang, Q., Liu, D., Majewski, P., Schulte, L.C., Korn, J.M.,
Young, R.A., Lander, E.S., and Hacohen, N.
The
Plasticity of Dendritic Cell Responses to Pathogens and Their
Components. Science 294:870-875 (2001).
Wilson, C.J., Guglielmo, C., Moua, N.D., Tudor, M., Grosveld,
G., Young, R.A. and Murray, P.J.
Yeast
artificial chromosome targeting technology: an approach for the
deletion of genes in the c57bl/6 mouse. Anal Biochem. 296:270-8
(2001).
Chen, C-H., Wang, T-L., Hung, C-F., Yang, Y., Chen, H., Young,
R.A., Pardoll, D.M. and Wu, T-C.
Enhancement
of DNA vaccine potency by linkage of antigen gene to an HSP70
gene. Cancer Research 60:1035-1042 (2000).
Cho, B.K., Palliser, D., Guillen, E., Wisniewski, J., Young,
R.A., Chen, J. and Eisen, H.N.
A
proposed mechanism for the induction of cytotoxic T lymphocyte
production by heat shock fusion proteins. Immunity 12:263-272
(2000).
Huang, Q., Richmond, J.F.L., Suzue, K., Eisen, H.N. and Young,
R.A.
Elicitation
of CTLs by Mycobacterial hsp70 Fusion Proteins Maps to a Discrete
Domain and is CD4+ T Cell-Independent. J. Exp. Med. 191:403-408
(2000).
Jabbar, I.A., Fernando, G.J.P., Saunders, N., Aldovini, A.,
Young, R., Malcolm, K. and Frazer, I.H.
Immune
responses induced by BCG recombinant for human papillomavirus L1
and E7 proteins. Vaccine 18:2444-2453 (2000).
Leung, N.J., Aldovini, A., Young, R., Jarvis, M.A., Smith,
J.M., Meyer, D., Anderson, D.E., Carlos, M.P., Gardner, M.B. and
Torres, J.V.
The
Kinetics of Specific Immune Responses in Rhesus Monkeys Inoculated
with Live Recombinant BCG Expressing SIV Gag, Pol, Env, and Nef
Proteins. Virology 268:94-103 (2000).
Nau, G.J., Chupp, G.L., Emile, J.F., Jouanguy, E., Berman,
J.S., Casanova, J.L. and Young, R.A.
Osteopontin
Expression Correlates with Clinical Outcome in Patients with
Mycobacterial Infection. Am J Pathol. 157:37-42
(2000).
Aldovini, A. and Young, R.A.
Recombinant BCG vaccines. in: Intracellular Bacteria as
Vaccines (Y. Patterson, ed.) J. Wiley and Sons, N.Y., N.Y.,
pp.151-169 (1999).
Murray, P.J. and Young, R.A.
Increased
anti-mycobacterial immunity in IL-10-deficient mice. Infect.
Immun. 67:3087-3095 (1999).
Nau, G.J., Liaw, L., Chupp, G.L., Berman, J.S., Hogan, B.L.M.
and Young, R.A.
Attenuated
Host Resistance Against Mycobacterium bovis BCG Infection in Mice
Lacking Osteopontin. Infect. Immun. 67:4223-4230
(1999).
Tsenova, L., Bergtold, A., Freedman, V.H., Young, R.A. and
Kaplan G.
Tumor
necrosis factor alpha is a determinant of pathogenesis and disease
progression in mycobacterial infection in the central nervous
system. Proc. Natl. Acad. Sci. USA 96:5657-5662
(1999).
Murray, P.J. and Young, R.A.
Secretion
of mammalian proteins from mycobacteria. Methods Mol. Biol.
101:275-284 (1998).
Murray, P.J., Young, R.A. and Daley, G.Q.
Hematopoietic
Remodeling in Interferon-{gamma}-Deficient Mice Infected With
Mycobacteria. Blood 91: 2914-2924 (1998).
Murray, P.J., Wang, L., Onufryk, C., Tepper, R.I. and Young,
R.A.
T
cell-derived IL-10 antagonizes macrophage function in
mycobacterial infection. J. Immunol. 158: 315-321
(1997).
Nau, G.J., Guilfoile, P., Chupp, G.L., Berman, J.S., Kim, S.J.,
Kornfeld, H. and Young, R.A.
A
chemoattractant cytokine associated with granulomas in
tuberculosis and silicosis. Proc. Natl. Acad. Sci. USA 94:
6414-6419 (1997).
Suzue, K., Zhou, X., Eisen, H.N. and Young, R.A.
Heat
shock fusion proteins as vehicles for antigen delivery into the
major histocompatibility complex class I presentation pathway.
Proc Natl Acad Sci USA 94: 13146-13151 (1997).
Murray, P.J., Aldovini, A. and Young, R.A.
Manipulation
and potentiation of antimycobacterial immunity using recombinant
BCG secreting cytokines. Proc. Natl. Acad. Sci. USA 93: 934-939
(1996).
Suzue, K. and Young, R.A.
Adjuvant-free
hsp70 fusion protein system elicits humoral and cellular immune
responses to HIV-1 p24. J. Immunol. 156: 873-879
(1996).
Suzue, K. and Young, R.A.
Heat
shock proteins as immunological carriers and vaccines. in:
Stress-Inducible Cellular Responses (U. Feige, R. I. Morimoto, I.
Yahara, B. S. Polla, eds.), Birkhauser/Springer, 77: 451-465
(1996).
Jindal, S., Murray, P., Rosenberg, S., Young, R.A. and
Williams, K.P.
Human
stress protein hsp70: Overexpression in E. coli, purification and
characterization. Biotechnology (NY) 13: 1105-1109
(1995).
Margolis, B. and Young, R.A.
Screening l expression
libraries with antibody and protein probes. in: DNA
Cloning-Expression Systems: A Practical Approach, Vol. II (B. D.
Hames and D. M. Glover, eds.) Oxford University Press, New York,
1-14 (1995).
Aldovini, A. and Young, R.A.
Construction and analysis of Human and Simian Immunodeficiency
Virus mutants. Methods Molecular Genetics 4: 3-17 (1994).
Jindal, S., Burke, E., Bettencourt, B., Khandekar, S., Young,
R.A. and Dwyer, D.S.
Human
hsp60: bacterial expression, purification, development of
monoclonal antibodies and a sandwich ELISA for quantitation.
Immunology Letters 39: 127-135 (1994).
O'Donnell, M., Aldovini, A., Duda, R.B., Yang, H., Szilvasi,
A., Young, R.A. and DeWolf, W.
Recombinant
Mycobacterium bovis BCG secreting functional Interleukin-2
enhances gamma interferon production by splenocytes. Infect.
Immun. 62: 2508-2514 (1994).
Tsomides, T.J., Aldovini, A., Johnson, R.P., Walker, B.D.,
Young, R.A. and Eisen, H.N.
Naturally
processed viral peptides recognized by cytotoxic T lymphocytes on
cells chronically infected by human immunodeficiency virus type 1.
J. Exp. Med. 180: 1283-1293 (1994).
Aldovini, A., Husson, R. and Young, R.A.
The
uraA locus and homologous recombination in Mycobacterium bovis
BCG. J. Bacteriol. 175: 7282-7289 (1993).
Aldovini, A., Young, R.A. and Palker, T.
New
AIDS vaccine candidates: antigen delivery and design. in: AIDS
'91, Vol. 5, (M.W. Adler, J.W.M. Gold and J.A. Levy, eds.),
Current Science Ltd., London, United Kingdom, pp. 153-160
(1992).
Aldovini, A. and Young, R.A.
The new vaccines. in: Technology Review, pp. 24-31
(1992).
Ferm, M.T., Soderstrom, K., Jindal, S., Gronberg, A., Ivanyi,
J., Young, R. and Kiessling, R.
Induction of human hsp60 expression in monocytic cell lines.
Intl. Immunol. 4: 305-311 (1992).
Jindal, S. and Young, R.A.
Vaccinia
virus infection induces a stress response that leads to
association of hsp70 with viral proteins. J. Virol. 66: 5357-5362
(1992).
Murray, P.J. and Young, R.A.
Stress
and immunological recognition in host-pathogen interactions. J.
Bacteriol. 174: 4193-4196 (1992).
Aldovini, A. and Young, R.A.
HIV1 virus-like particles as a source of antigen for AIDS
vaccines. in: Vaccine Research: A Series of Advances (W. Koff and
H. Six, eds.), Marcel Dekker, Inc., New York, pp. 43-50
(1991).
Aldovini, A. and Young, R.A.
Humoral
and cell-mediated immune responses to live recombinant BCG-HIV
vaccines. Nature 351: 479-482 (1991).
Jindal, S. and Young, R.A.
Immune recognition of stress proteins in infection and in
surveillance of stressed cells. in: Heat Shock (B. Maresca and S.
Lindquist, eds.), Springer-Verlag, Heidelberg, pp. 193-202
(1991).
Young, R.A. and Davis, R.W.
Gene
isolation with the lambda gt11 system. Methods Enzymol. 194:
230-238 (1991).