1999

Aldovini, A. and Young, R.A.
Recombinant BCG vaccines.
in: Intracellular Bacteria as Vaccines(Y. Patterson, ed.)
J. Wiley and Sons, N.Y., N.Y., pp.151-169(1999).

Holstege, F.C.P. and Young, R.A.
Transcriptional regulation: Contending with Complexity.
Proc. Natl. Acad. Sci. USA 96:2-4 (1999).
[ABSTRACT] [FREE FULL TEXT]

Jennings, E.G. and Young, R.A.
Genome expression on the World Wide Web.
Trends Genet. 15:202-204 (1999).
[ABSTRACT] [FULL TEXT]

Kimmelman, J., Kaldis, P., Hengartner, C.J., Laff, G.M., Koh, S.S., Young, R.A. and Solomon, M.J.
Activating Phosphorylation of the Kin28p Subunit of TFIIH by the Cdk Activating Kinase, Cak1p.
Mol. Cell. Biol. 19:4774-4787 (1999).
[ABSTRACT] [FREE FULL TEXT]

Kobor, M.S., Archambault, J., Lester, W., Holstege, F.C.P., Gileadi, O., Jansma, D., Jennings, E.G., Kouyoumdjian, F., Davidson, A.R., Young, R.A. and Greenblatt, J.
A Novel Protein Phosphatase Required for Dephosphorylation of the CTD and Transcription by RNA polymerase II in Saccharomyces cerevisiae.
Mol. Cell 4:55-62 (1999).
[ABSTRACT] [FULL TEXT]

Murray, P.J. and Young, R.A.
Increased anti-mycobacterial immunity in IL-10-deficient mice.
Infect. Immun. 67:3087-3095 (1999).
[ABSTRACT] [FREE FULL TEXT]

Nau, G.J., Liaw, L., Chupp, G.L., Berman, J.S., Hogan, B.L.M. and Young, R.A.
Attenuated Host Resistance Against Mycobacterium bovis BCG Infection in Mice Lacking Osteopontin.
Infect. Immun. 67:4223-4230 (1999).
[ABSTRACT] [FREE FULL TEXT]

Tsenova, L., Bergtold, A., Freedman, V.H., Young, R.A. and Kaplan G.
Tumor necrosis factor alpha is a determinant of pathogenesis and disease progression in mycobacterial infection in the central nervous system.
Proc. Natl. Acad. Sci. USA 96:5657-5662 (1999).
[FREE FULL TEXT]

Tudor, M., Murray, P.J., Onufryk, C., Jaenisch, R. and Young, R.A.
Ubiquitous Expression and Embryonic Requirement for RNA Polymerase II Coactivator Subunit Srb7 in Mice.
Genes Dev. 13:2365-2368 (1999).
[ABSTRACT] [FREE FULL TEXT]

Viljoen, M., Volschenk, H., Young, R.A. and van Vuuren, H.J.J.
Transcriptional Regulation of the Schizosaccharomyces pombe Malic Enzyme Gene, mae2.
J. Biol. Chem. 274:9969-9975 (1999).
[ABSTRACT] [FREE FULL TEXT]

Wyrick, J.J., Holstege, F.C.P., Jennings, E.G., Causton, H.C., Shore, D., Grunstein, M., Lander, E.S. and Young, R.A.
Chromosomal Landscape of Nucleosome-dependent Gene Expression and Silencing in Yeast.
Nature 402:418-421 (1999).
[ABSTRACT] [FULL TEXT]

TOP


1998

Apone, L.M., Virbasius, C.A., Holstege, F.C.P., Wang, J., Young, R.A. and Green, M.R.
Broad, but Not Universal, Transcriptional Requirement for yTAFII17, a Histone H3-like TAFII Present in TFIID and SAGA.
Mol. Cell 2:653-661 (1998).
[ABSTRACT] [FULL TEXT]

Hengartner, C.J., Myer, V.E., Liao, S.-M., Wilson, C.J., Koh, S.S. and Young, R.A.
Temporal Regulation of RNA Polymerase II by Srb10 and Kin28 Cyclin-Dependent Kinases.
Mol. Cell 2:43-53 (1998).
[ABSTRACT] [FULL TEXT]

Holstege, F.C.P., Jennings, E.G., Wyrick, J.J., Lee, T., Hengartner, C.J., Green, M.R., Golub, T.R., Lander, E.S. and Young, R.A.
Dissecting the Regulatory Circuitry of a Eukaryotic Genome.
Cell 95:717-728 (1998).
[ABSTRACT] [FULL TEXT] [WEBSITE]

Koh, S.S., Ansari, A.Z., Ptashne, M. and Young, R.A.
An Activator Target in the RNA Polymerase II Holoenzyme.
Mol. Cell 1:895-904 (1998).
[ABSTRACT] [FULL TEXT]

Lee, T., Wyrick, J.J., Koh, S.S., Jennings, E.G., Gadbois, E.L. and Young, R.A.
Interplay of Positive and Negative Regulators in Transcription Initiation by RNA Polymerase II Holoenzyme.
Mol. Cell. Biol. 18:4455-4462 (1998).
[ABSTRACT] [FREE FULL TEXT]

Lee, T. and Young, R.A.
Regulation of Gene Expression by TBP-associated Proteins.
Genes Dev. 12:1398-1408 (1998).
[FREE FULL TEXT]

Murray, P.J. and Young, R.A.
Secretion of mammalian proteins from mycobacteria.
Methods Mol. Biol. 101:275-284 (1998).
[ABSTRACT]

Murray, P.J., Young, R.A. and Daley, G.Q.
Hematopoietic Remodeling in Interferon-{gamma}-Deficient Mice Infected With Mycobacteria.
Blood 91: 2914-2924 (1998).
[ABSTRACT] [FREE FULL TEXT]

Myer, V.E. and Young, R.A.
RNA Polymerase II Holoenzymes and Subcomplexes.
J. Biol. Chem. 273:27757-27760 (1998).
[ABSTRACT] [FREE FULL TEXT]

Parvin, J.D. and Young, R.A.
Regulatory Targets in the RNA Polymerase II Holoenzyme.
Curr. Op. Genet. Dev. 8:565-570 (1998).
[ABSTRACT]


TOP


1997
Gadbois, E.L., Chao, D.M., Reese, J.C., Green, M.R. and Young, R.A.
Functional antagonism between RNA polymerase II holoenzyme and global negative regulator NC2 in vivo.
Proc. Natl. Acad. Sci. USA 94: 3145-3150 (1997).
[ABSTRACT] [FREE FULL TEXT]

Koh, S.S., Hengartner, C.J. and Young, R.A.
Baculoviral transfer vectors for expression of FLAG fusion proteins in insect cells.
Biotechniques 23:622-624 (1997).
[ABSTRACT]

Murray, P.J., Wang, L., Onufryk, C., Tepper, R.I. and Young, R.A.
T cell-derived IL-10 antagonizes macrophage function in mycobacterial infection.
J. Immunol. 158: 315-321 (1997).
[ABSTRACT]

Nau, G.J., Guilfoile, P., Chupp, G.L., Berman, J.S., Kim, S.J., Kornfeld, H. and Young, R.A.
A chemoattractant cytokine associated with granulomas in tuberculosis and silicosis.
Proc. Natl. Acad. Sci. USA 94: 6414-6419 (1997).
[ABSTRACT]

Qin, J., Fenyo, D., Zhao, Y., Hall, W.W., Chao, D.M., Wilson, C.J., Young, R.A. and Chait, B.T.
A strategy for rapid, high-confidence protein identification.
Anal Chem 69:3995-4001 (1997).
[ABSTRACT]

Scully, R., Anderson, S.F., Chao, D.M., Wei, W., Ye, L., Young, R.A., Livingston, D.M. and Parvin, J.D.
BRCA1 is a component of the RNA polymerase II holoenzyme.
Proc. Natl. Acad. Sci. USA 94: 5605-5610 (1997).
[ABSTRACT] [FREE FULL TEXT]

Suñé, C., Hayashi, T., Liu, Y., Lane, W.S., Young, R.A. and Garcia-Blanco, M.A.
CA150, a nuclear protein associated with the RNA polymerase II holoenzyme, is involved in Tat-activated human immunodeficiency virus type 1 transcription.
Mol Cell Biol 17: 6029-6039 (1997).
[ABSTRACT] [FREE FULL TEXT]

Suzue, K., Zhou, X., Eisen, H.N. and Young, R.A.
Heat shock fusion proteins as vehicles for antigen delivery into the major histocompatibility complex class I presentation pathway.
Proc Natl Acad Sci USA 94: 13146-13151 (1997).
[ABSTRACT] [FREE FULL TEXT]

Volschenk, H., Viljoen, M., Grobler, J., Petzold, B., Bauer, F., Subden, R.E., Young, R.A., Lonvaud, A., Denayrolles, M. and van Vuuren, H.J.
Engineering pathways for malate degradation in Saccharomyces cerevisiae.
Nat Biotechnol 15: 253-257 (1997).
[ABSTRACT]


TOP


1996

Chao, D.M., Gadbois, E.L., Murray, P.J., Anderson, S.F., Sonu, M.S., Parvin, J.D., and Young, R.A.
A mammalian SRB protein associated with an RNA polymerase II holoenzyme.
Nature 380: 82-85 (1996).
[ABSTRACT]

Chao, D.M. and Young, R.A.
Activation without a vital ingredient.
Nature 383: 119-120 (1996).
[ABSTRACT]

Koleske, A.J., Chao, D.M. and Young, R.A.
Purification of RNA polymerase II holoenzymes.
Methods Enzymol. 273: 176-184 (1996).
[ABSTRACT]

Murray, P.J., Aldovini, A. and Young, R.A.
Manipulation and potentiation of antimycobacterial immunity using recombinant BCG secreting cytokines.
Proc. Natl. Acad. Sci. USA 93: 934-939 (1996).
[ABSTRACT] [FREE FULL TEXT]

Rubin, D.M., Coux, O., Wefes, I., Hengartner, C., Young, R.A., Goldberg, A.L. and Finley, D.
Identification of the gal4 suppressor Sug1 as a subunit of the yeast 26S proteosome.
Nature 374: 655-657 (1996).
[ABSTRACT]

Suzue, K. and Young, R.A.
Adjuvant-free hsp70 fusion protein system elicits humoral and cellular immune responses to HIV-1 p24.
J. Immunol. 156: 873-879 (1996).
[ABSTRACT]

Suzue, K. and Young, R.A.
Heat shock proteins as immunological carriers and vaccines.
in: Stress-Inducible Cellular Responses (U. Feige, R. I. Morimoto, I. Yahara, B. S. Polla, eds.)
Birkhauser/Springer, 77: 451-465 (1996).
[ABSTRACT]

Wilson, C.J., Chao, D.M., Imbalzano, A.N., Schnitzler, G.R., Kingston, R.E. and Young, R.A.
RNA polymerase II holoenzyme contains SWI/SNF coactivators involved in chromatin remodeling.
Cell 84: 235-244 (1996).
[ABSTRACT]